Fig. 4From: Preclinical studies on the toxicology, pharmacokinetics and safety of K1-70TM a human monoclonal autoantibody to the TSH receptor with TSH antagonist activitya Normal thyroid histology in a control cynomolgus monkey (×0.7 magnification). Reproduced with permission of the copyright holder, AV7 Ltd. b Cynomolgus monkey thyroid histology after K1-70™ treatment (×0.6 magnification) showing thyroid cystic follicles. There was increased severity of cystic follicles in the thyroids of male cynomolgus monkeys treated IV with K1-70™. Reproduced with permission of the copyright holder, AV7 LtdBack to article page