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Fig. 2 | Autoimmunity Highlights

Fig. 2

From: Anti-β2-glycoprotein I and anti-phosphatidylserine/prothrombin antibodies exert similar pro-thrombotic effects in peripheral blood monocytes and endothelial cells

Fig. 2

TF mRNA relative expression levels in monocytes obtained from PBMCs of five BD stimulated as described below for 4 h. PT was added in all cases, while LPS (1 ng/ml) was added alone or followed by the IgG fractions (0.5 mg/ml) extracted from three BD or aPL + patients disclosing aβ2GpI positive antibodies (three pooled sera) or aPS/PT positive antibodies (three pooled sera). The bars represent the mean ± SD of three independent experiments. The expression levels of mRNA were detected by PCR real-time with ΔΔct method. *p < 0.05, **p < 0.001

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