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Fig. 3 | Autoimmunity Highlights

Fig. 3

From: Induction of IL-10 cytokine and the suppression of T cell proliferation by specific peptides from red cell band 3 and in vivo effects of these peptides on autoimmune hemolytic anemia in NZB mice

Fig. 3

IL-10 production and CD4 T cell proliferation elicited by selected band 3 peptides. The peptides were selected according to their ability to induce IL-10 production. CD4 T cell were stimulated with selected peptides at a dose of 200 μg/ml and IL-10 production was calculated by CelELISA (a) and stimulation index of proliferative response was measured by incorporation of [3H] thymidine (b). T cell proliferation as assessed from day 3 to day 6 after co-culture with peptides. The proliferative response is expressed as a stimulation index (SI) calculated by dividing the mean cpm of peptide-stimulated wells by the mean cpm of non-stimulated wells. The data shown are means of duplicate samples representative of three independent experiments

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Autoimmunity Highlights

ISSN: 2038-3274

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