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Table 2 Anti-cN-1A reactivity in sera from patients with sporadic inclusion body myositis (sIBM) and in healthy controls as determined by anti-cN-1A IgG ELISA at the Institute for Experimental Immunology (Lübeck, Germany)

From: Development and evaluation of a standardized ELISA for the determination of autoantibodies against cN-1A (Mup44, NT5C1A) in sporadic inclusion body myositis

Cohorts

n

Anti-cN-1A ELISA (IgG)

Positive

Negative

Sensitivity (CI 95%)

Specificity (CI 95%)

sIBM

51

20

31

39.2% (27.0–52.9%)

 

Healthy controls

202

7

195

 

96.5% (92.9–98.5%)

  1. CI confidence interval, cN-1A cytosolic 5′-nucleotidase 1A, sIBM sporadic inclusion body myositis