Table 2 Time evolution of two-step strategy for NCA/ANA detection/measurement
From: Automation, consolidation, and integration in autoimmune diagnostics
Era | Years | Methods |
|---|---|---|
Manual ANA IIF–reflective adding on–manual ENA | 1970–2000 | Manual IIF Manual monoplex methods Low automated monoplex methods |
Manual ANA IIF–reflective adding on–automated ENA | 2000–2014 | Manual IIF Full automated monoplex methods Low automated multiplex methods |
Automated ANA IIF–reflex adding on–automated ENA | 2015–… | Automated IIF Full automated monoplex methods Full automated multiplex methods |