Fig. 6

DNase activity in sera from healthy individuals (CTR), RA and RRMS patients. The SRED method was used to determine the DNase activity in the sera. Sera were applied to wells in a 1.4 % agarose gel containing DNA and a DNA-staining dye and incubated in a humidified chamber at 37 °C for 24 h. Subsequently, the radius of the non-fluorescent area surrounding each well was measured