Table 1 Bohan and Peter’s polymyositis and dermatomyositis diagnostic criteria
From: Assessment of patients with idiopathic inflammatory myopathies and isolated creatin-kinase elevation
1. Symmetric proximal muscle weakness determined by physical examination |
2. Elevation of serum skeletal muscle enzymes, including CK, aldolase, serum glutamate oxaloacetate and pyruvate transaminases, and lactate dehydrogenase |
3. The electromyographic triad of short, small, polyphasic motor unit potentials; fibrillations, positive sharp waves, and insertional irritability; and bizarre, high-frequency repetitive discharges |
4. Muscle biopsy abnormalities of degeneration, regeneration, necrosis, phagocytosis, and an interstitial mononuclear infiltrate |
5. Typical skin rash of DM. Including a heliotrope rash and Gottron’s sign/papules |