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Table 1 Frequency of anti-Sm, anti-U1snRNP, anti-Ro/SS-A, anti-La/SS-B, anti-Jo-1(histRNA-Synthetase) and anti-Scl-70(Topoisomerase I) autoantibodies in patient sera

From: Efficiency of a solid-phase chemiluminescence immunoassay for detection of antinuclear and cytoplasmic autoantibodies compared with gold standard immunoprecipitation

 

anti-U1snRNP

anti-Sm

anti-Ro/SS-A

anti-La/SS-B

anti-Jo-1

anti-Scl-70

Other anti-rRNP

SLE (n = 42)

19

6

30

13

0

0

7

 SLE + SS (n = 11)

1

1

11

7

0

0

0

 SLE + RD (n = 5)

4

0

1

1

0

0

0

 SLE + NS (n = 8)

9

1

2

1

0

0

6

 SLE + APS (n = 3)

2

0

0

0

0

0

2 (NS)

SS (n = 24)

1

0

24

11

0

0

0

 SS + RA (n = 3)

0

0

3

2

0

0

0

 SS + APS (n = 2)

0

0

2

0

0

0

0

 SS + PBC (n = 3)

0

0

3

0

0

0

0

PM (n = 4)

0

0

3

0

4

0

0

 PM + SS (n = 1)

0

0

1

0

1

0

0

ASS (n = 1)

0

0

1

0

1

0

0

SSc (n = 11)

4

0

0

0

0

10

0

MCTD (n = 3)

3

0

0

0

0

0

0

Other (n = 13)

6

0

7

0

0

0

0

NHS (n = 16)

0

0

0

0

0

0

0

Prevalence

27.8 %

6.7 %

56.7 %

23 %

4.8 %

9.6 %

 
  1. Gold standard techniques were used to calculate the frequency of autoantibodies in our cohort of patient sera. The left column shows the diagnosis and number of the patient sera analyzed. The second column shows the number of patients with more than one associated autoimmune disease
  2. SLE systemic lupus erythematosus, SS Sjögren’s syndrome, RD renal disease, NS neurological syndrome, APS antiphospolipid syndrome, RA rheumatoid arthritis, PBC primary biliary cirrhosis, PM polymyositis, ASS antisynthetase syndrome, SSc systemic sclerosis, MCTD mixed connective tissue disease, NHS normal human sera