A rare combination of type 3 autoimmune polyendocrine syndrome (APS-3) or multiple autoimmune syndrome (MAS-3)

Autoimmunity Highlights

Table 1 Classification of autoimmune polyendocrine syndromes (APS) modified from Neufeld [1]

APS-1 or APECED (autoimmune-poly-endocrine-candidiasis-ectodermal-dystrophy)	Chronic mucocutaneous candidiasis
	Chronic hypoparathyroidism
	Addison’s disease (at least two out of three)
APS-2 or Schmidt’s syndrome	Addison’s diseases + thyroid autoimmune disease and/or diabetes mellitus type 1
APS-3 (excluding Addison’s disease)	Thyroid autoimmune disease + DM-1: Type 3A
	Chronic atrophic gastritis or pernicious anemia: Type 3B
	Vitiligo, alopecia or myasthenia gravis: Type 3C
APS-4	Any other possible association of autoimmune diseases

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