From: Detection of autoantibodies in a point-of-care rheumatology setting
Autoantibody | Detection technology/assay platform | Assay duration | References |
---|---|---|---|
Anti-dsDNA | Electrochemical reduction of redox-tagged probe/Ab inhibition in single-step cell | ~45Â min | [60] |
Decreased resonance frequency/piezoelectric quartz crystal microbalance | <60Â min | [61] | |
Refractive index change/surface plasmon resonance sensor chip | ~5Â min | [62] | |
Anti-CCP | Formation of visual line by colored nanoparticles/lateral flow chromatography | 10Â min | [66] |
Refractive index change/surface plasmon resonance sensor chip | ~5Â min | [67] | |
Anti-chromatin | Peroxidase-mediated electrochemical amplification/flow-through cell | 20Â min | [64] |
Anti-IgG (RF) Anti-MCV | Formation of visual line by colored nanoparticles/lateral flow chromatography | 15Â min | [65] |
Anti-Ro/SSA, Anti-Ro52, Anti-La/SSB | Luminescence by luciferase-tagged probe/bead immobilized Ab in two-step cells | 25Â min | [63] |
Anti-β2-glyco-protein I | Refractive index change/surface plasmon resonance sensor chip | ~5 min | [68] |