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Table 3 Distribution of CD and UC patients in relation to arthritis and their activity

From: Interleukin-1 associations in inflammatory bowel disease and the enteropathic seronegative spondylarthritis

 

aCD/aeSpA

aCD/ieSpA

iCD/aeSpA

iCD/ieSpA

aUC/aeSpA

aUC/ieSpA

iUC/aeSpA

iUC/ieSpA

Patients (N)

5

15

0

14

4

16

0

6

Sex (M/F)

4/1

10/5

0

8/6

4/0

7/9

4/2

Age

 Median [range]

35 [20–61]

27 [18–46]

36.5 [18–56]

34 [30–63]

37.5 [23–65]

65 [23–70]

Disease duration

 Median [range]

3 [2–6]

2 [0.2–20]

2 [0.1–11]

4.5 [1–10]

2 [0.1–20]

7.5 [0.4–30]

CDAI

 Median [range]

200 [130–237]

100 [12–400]

75.5 [20–150]

5.5 [4–8]

4 [1–7]

1 [0–2]

BASDAI

 Median [range]

4.7 [1.2–5.2]

2.4 [1.6–3.2]

3 [1.8–3.8]

4 [3.7–6.4]

1.2

1.1 [0.8–1.4]

CRP

 Median [range]

8.3 [6–32]

6.8 [0.2–82.4]

0.9 [0.18–27]

10.3 [4–145]

5.9 [0.3–14.6]

0.5 [0.46–2.6]

Cytokines (pg/ml)

IL-1α

 Median [range]

3.9 [3.9–118.4]

14.6 [3.9-250]

3.9 [3.9–250]

3.9 [3.9–3.9]

9.1 [3.9–250]

3.9 [3.9–7.63]

IL-1β

 Median [range]

3.7 [2.5–15.3]

4 [2.2–17.1]

4.1 [2.5–27.7]

36.4 [3.7–58]

3.2 [1.8–244]

2.3 [1.8–3.7]

IL-1Ra

 Median [range]

21.1 [12.7–186]

16.9 [10.6–70.8]

16.9 [12.7–119.9]

91.3 [16.9–260]

14.8 [10.6–1,671]

12.7 [12.7–16.9]

TNFα

 Median [range]

8 [0.8–49]

3 [0–13]

4.3 [0–22.4]

2.2 [0–10.8]

4.3 [0–17.1]

3.9 [0–5.1]

  1. aCD active Crohn’s disease, iCD inactive Crohn’s disease, aUC active ulcerative colitis, iUC inactive ulcerative colitis, aeSpA active enteropathic spondylarthritis, ieSpA inactive enteropathic spondylarthritis