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Table 1 Characteristics of coupled antigens in Zenit RA reagents

From: Routine use of Zenit RA, a novel chemiluminescent immunoanalyzer in autoimmune disease diagnosis

Analytes

Nature of antigens

ds-DNA

PCR product

SSA 60 + 52 kDa

Recombinant protein

SSB

48 kDa recombinant protein

Sm

Protein native purified mix of subunits D, B, E, F, G

RNP

Recombinant RNP 70 kDa, RNP A 34 kDa and RNP C 25 kDa

Scl70

72 kDa recombinant protein

Jo1

58 kDa recombinant protein

Cardiolipin

Bovine cardiolipin and human β2-glycoprotein 1 protein

β2 Glycoprotein 1

Human β2-glycoprotein 1 protein

MPO

Purified protein from human neutrophils

PR3

Purified protein from human neutrophils

CCP

Second generation synthetic peptide

  1. ZENIT RA ENA Screen: screening panel contains nine different kinds of microparticles: SSA52, SSA60, SSb, Sm, RNP70 kDa, RNP A 34 kDa, RNP C 25 kDa, Scl-70 72 kDa, Jo-1 58 kDa