Fig. 1
From: The perspective on standardisation and harmonisation: the viewpoint of the EASI president
The effect of pool-sera in relation to individual test results. If equal amounts of 4 samples with different reactivities (10, 20, 30 and 40 AU/mL; blue diamonds) in 2 immuno-assays are mixed, the pool-serum probably will reveal the average reactivity (25 AU/mL; red circle) in both assays. If both assays would be calibrated on this pool-serum, the individual test results of the 4 samples will remain different. This obviously also holds for megapools