From: Receptor autoimmunity: diagnostic and therapeutic implications
Autoantibody | Acronym | Subclasses | Action |
---|---|---|---|
TSH receptor antibodies | TRAb | IgG | Stimulating TSH receptor Blocking TSH receptor Apoptosis of thyrocyte |
Acetylcholine receptor antibodies | ACHRAb | IgG 1, IgG 3 | Disruption of receptor signaling Complement-dependent internalization of receptor |
N-methyl-d-aspartate receptor antibodies | NMDARAb | IgG, IgA, IgM | Crosslinking and internalization of receptor |
Phospholipase 2 receptor antibodies | PLAR2Ab | IgG | Thickening of capillary wall |