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Table 1 Main HLA associations with IgG4-mediated neurological diseases

From: Associations between HLA and autoimmune neurological diseases with autoantibodies

Autoantibody

HLA

Carriers

References

Anti-Musk

DQB1*05

78%

[61]

DQB1*05-DRB1*14

26%

[61]

DQB1*05-DRB1*16

20%

[61]

Anti-NF

DRB1*15

77%

[69]

Anti-IgLON5

DQB1*05:01-DRB1*10:01

57–90%

[70, 71, 76]

DQA1*01-DQB1*05

≈ 90%

[76]

Anti-LGI1

DRB1*07:01

≈ 90%

[84,85,86]

Anti-CASPR2

DRB1*11:01

48%

[86]

  1. CASPR2 Contactin-associated protein-like 2, HLA Human leukocyte antigen, LGI1 leucine-rich glioma-inactivated 1, MusK muscle-specific tyrosine kinase, NF neurofascin 155