Table 10 Toxicokinetic parameters of K1-70™ in male and female monkeys following IM administration of K1-70™
Day | K1-70™ dose (mg/dose) | Sex | Cmax (µg/mL) | tmax (h) | AUC(0–t) (µg h/mL) |
|---|---|---|---|---|---|
1 | 5 | M | 13.3 | 72.0 | 2020 |
F | 16.9 | 72.0 | 2600 | ||
22 | 5 | M | 56.8 | 24.0 | 6620 |
F | 48.5 | 24.0 | 7490 |