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Table 2 Individual diagnoses of patients within each diagnostic group

From: The clinical significance of atypical indirect immunofluorescence patterns on primate cerebellum in paraneoplastic antibody screening

(Auto-) immune-mediated diseases (18; 11.1%)

Epilepsy (46; 28.4%)

Inflammatory/infectious CNS diseases (13; 8%)

Movement disorders (14; 8.6%)

Neurocognitive disorders (14; 8.6%)

Neuromuscular diseases (3; 1.9%)

Peripheral (poly-) neuropathies (33; 20.4%)

PNS (6; 3.7%)

Tumor-related diagnoses (15; 9.3%)

ALPSa

Absence seizures

Encephalopathy

Cerebellar ataxia (4)

Alzheimer’s (4)

ALS (3)

CIDP (9)

Burkitt lymphoma: encephalitis

Adenocarcinoma: CIDP

Anti-VGKC LE (4)

Unspecified EP (8)

Irradiation leuko-encephalopathy

Cerebellar syndrome

Frontal network syndrome

 

Demyelinating motoric PNP

Hodgkin’s lymphoma: CD

Adenocarcinoma: MC

AI encephalitis (2)

Focal EP (5)

Meningitis

Cerebellar-pyramidal syndrome

Frontotemporal degeneration

 

Diabetic PNP (2)

Lung adenoma: anti-VGKC LE

Acute myeloid leukemia

AI PNP (2)

Generalized EP (8)

Myelitis transversa

Chorea-atotic syndrome

Frontotemporal dementia

 

Guillain-Barré syndrome (4)

Mammary carcinoma: cerebellar ataxia

Angiomyolipoma: de novo EP

Hypophysitis (lymphocytic)

Lesional EP (3)

Myelitis transversa + meningo-encephalitis

Multiple system atrophy (3)

Lewy body disease

 

Miller-Fisher syndrome

Small-cell lung cancer: LE

Cervix carcinoma: de novo EP

Multiple sclerosis

Temporal lobe EP (21)

Myelopathy (Vit. B12 deficiency)

PSP (2)

Multidomain mild cognitive impairment

 

Mononeuritis multiplex

Thymoma: anti-GAD LE

Ependymoma: compartment syndrome

Myasthenia gravis

 

N. Trigeminus failure

SPS (2)

Normal-pressure hydrocephalus

 

Motor PNP

 

Glioma

Myelitis transversa + NMO

 

Neurosarcoidosis

 

Psychosis (4)

 

Sensory PNP (2)

 

Lung carcinoma: MC (2)

PERM

 

Viral encephalitis (5)

   

Sensorimotor PNP (10)

 

Mammary carcinoma: hypermetropia and presbyopia

Polymyositis

     

SFNP (2)

 

Melanoma: myelitis

Ramsay Hunt syndrome

       

Neuroblastoma

Seronegative LEb (2)

       

Ovarium carcinoma (2)

        

Pancreas carcinoma: CIDP

  1. X:Y diagnosis Y associated with cancer X, AI autoimmune, ALPS autoimmune lymphoproliferative syndrome, ALS amyotrophic lateral sclerosis, CD cerebellar degeneration, CIDP chronic inflammatory demyelinating polyneuropathy, EP epilepsy, LE limbic encephalitis, MC meningitis carcinomatosa, NMO neuromyelitis optica, PERM progressive encephalomyelitis with rigidity and myoclonus, PNP polyneuropathy, PSP progressive supranuclear palsy, SFNP small-fiber polyneuropathy, SPS Stiff–Person syndrome
  2. aNumber of patients diagnosed with the disease, 1 patient when not specified
  3. bDiagnosis based on clinical symptoms and treatment effect
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Autoimmunity Highlights

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