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Fig. 4 | Autoimmunity Highlights

Fig. 4

From: Anti-β2-glycoprotein I and anti-phosphatidylserine/prothrombin antibodies exert similar pro-thrombotic effects in peripheral blood monocytes and endothelial cells

Fig. 4

NO production in HUVEC. Cells were stimulated for sixteen hours with LPS (1 ng/ml) alone or with the IgG fractions (0.5 mg/ml) extracted from three BD or aPL + patients disclosing aβ2GpI positive antibodies (three pooled sera) or aPS/PT positive antibodies (three pooled sera). The bars represent the mean ± SD of three independent experiments. NOx levels were measured in supernatant of untreated and treated-cells. *p < 0.05, **p < 0.001

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