Fig. 1

a Conventional algorithm used in HUMV (Spain). Abbreviations (H, Sp, Nuc, Cent, Dense fine sp.) refer to the different patterns found in ANA IIF test on HEp-2 cells: homogeneous, speckled, nucleolar, centromere and dense fine speckled. SARD Systemic autoimmune rheumatic diseases. b New algorithm including anti-DFS70 antibody detection. Abbreviations (H, Sp, Nuc, Cent, Dense fine sp.) made reference to the different patterns found in ANA IIF test on HEp-2 cells: homogeneous, speckled, nucleolar, centromere and dense fine speckled. SARD Systemic autoimmune rheumatic diseases