Table 3 ANA-reflex test procedure with patterns related to markers found in autoimmune liver diseases
From: The ANA-reflex test as a model for improving clinical appropriateness in autoimmune diagnostics
ANA-IIF pattern on HEp-2 cells | Reflex test(s) |
|---|---|
Cytoplasmic reticular/AMA ≥1:160 | Anti-mitochondrial M2 or E3 or MIT3 |
Multiple nuclear dots ≥1:160 | Anti-Sp100 |
Nuclear envelope | Anti-gp210 |
Cytoplasmic linear-actin ≥1:160 | IIF on kidney, stomach, and liver, to confirm anti-actin antibodies |