| Giant capillaries | Neoangiogenesis | Avascular areas | Density |
---|---|---|---|---|
Females vs males | 3.0 (1–19) vs 6.0 (3–9) | 2.5 (0–10) vs 4.2 (0–8) | 1.5 (0–10) vs 1.1 (0–3) | 6.2 (2.3–14.5) vs 6.9 (5.9–7.9) |
Diffuse vs limited | 3.0 (1–11) vs 3.1 (1–19) | 1.0 (0–8) vs 2.7 (0–10) | 2.0 (0–10) vs 1.2 (0–9) | 5.2 (2.3–14.5) vs 6.5 (3.0–12) |
Anti-Scl70 vs ACA | 1.8 (1–11) vs 3.4 (1–19) | 2.8 (0–8) vs 2.7 (0–10) | 1.8 (0–10) vs 1.5 (0–9) | 4.9 (2.3–8.8) vs 6.1 (2.4–14.5) |
Anti-Scl70 vs others | 1.8 (1–11) vs 8.7 (1–19) | 2.8 (0–8) vs 1.4 (0–10) | 1.8 (0–10) vs 0.5 (0–2) | 4.9 (2.3–8.8) vs 7.5 (4.0–14.5) |
ACA vs others | 3.4 (1–19) vs 8.7 (1–19) | 2.7 (0–10) vs 1.4 (0–10) | 1.5 (0–10) vs 0.5 (0–2) | 6.1 (2.3–14.5) vs 7.5 (4.0–14.5) |
No ulcers vs ulcers | 3.2 (1–18) vs 3.0 (1–19) | 2.7 (0–8) vs 2.0 (0–10) | 1.5 (0–10) vs 1.4 (0–5) | 6.1 (2.3–14.5) vs 5.9 (4.0–9.8) |
No GE vs GE | 5.7 (1–17) vs 2.8 (1–19) | 1.6 (0–3) vs 3.0 (0–10) | 1.0 (0–4) vs 1.5 (0–10) | 6.9 (3.0–9.4) vs 6.0 (2.3–14.5) |
sPAP < 45 mmHg vs > 45 mmHg | 3.3 (1–19) vs 2.0 (1–3) | 2.4 (0–10) vs 6.5 (0–8) | 1.2 (0–9) vs 4.3 (2–10)* | 6.3 (2.4–14.5) vs 5.2 (2.3–5.9) |
DLCO < 50 % vs > 50 % | 2.5 (1–7) vs 4.1 (1–19) | 5.0 (0–8) vs 2.7 (0–10) | 1.5 (0–4) vs 1.2 (0–10) | 5.3 (4.6–14.5) vs 6.1 (2.3–12) |
FVC < 80 % vs > 80 % | 3.4 (1–19) vs 3.0 (2–9) | 2.7 (0–10) vs 2.4 (0–8) | 0.9 (0–9) vs 2.1 (0–10) | 6.5 (2.3–14.5) vs 5.3 (2.3–7.9) |
No honeycombing vs honeycombing | 3.6 (1–19) vs 2.3 (1–3) | 1.5 (0–10) vs 5.0 (1–6) | 0.7 (0–4) vs 1.2 (0–10) | 6.3 (4.0–9.9) vs 5.0 (2.3–14.5) |
Skin score < 14 vs > 14 | 3.0 (1–19) vs 8.0 (1–11) | 2.7 (0–10) vs 1.2 (0–8) | 1.4 (0–9) vs 1.8 (0–10) | 6.6 (2.4–12.0) vs 4.6 (2.3–14.5) |
No iloprost vs iloprost | 3.6 (1–19) vs 3.0 (1–16) | 2.0 (0–8) vs 3.0 (0–10) | 0.7 (0–3.4) vs 1.5 (0–10)* | 6.1 (4.0–9.9) vs 6.1 (2.3–14.5) |
No bosentan vs bosentan | 3.4 (1–19) vs 2.0 (1–6) | 1.8 (0–10) vs 5.8 (3–8)* | 0.9 (0–10) vs 1.8 (2–4) | 6.3 (2.3–14.5) vs 5.6 (5.0–8.8) |
Early pattern vs others | 0.5 (1–4) vs 3.3 (1–19)* | 3.1 (1–10) vs 2.2 (0–10) | 0.5 (0–1) vs 1.5 (0–10)* | 9.5 (9.0–10.8) vs 5.9 (2.3–14.5)* |
Active pattern vs others | 8.0 (1–19) vs 1.6 (1–8)* | 2.0 (0–10) vs 3.0 (0–10) | 0.7 (0–3) vs 2.0 (0–10)* | 6.9 (4.0–14.5) vs 5.3 (2.3–12.0) |
Late pattern vs others | 2.1 (1–7) vs 6.3 (1–19)* | 2.7 (0–8) vs 2.4 (0–10) | 2.1 (1–10) vs 0.5 (0–3)* | 5.0 (2.3–9.8) vs 7.5 (4.0–14.5)* |
VEGF-A <0.8U vs >0.8U | 3.0 (1–19) vs 3.8 (1–9) | 2.0 (0–10) vs 4.5 (0–6) | 1.5 (0–10) vs 1.5 (0–3) | 6.4 (2.3–12.0) vs 4.7 (4.0–14.5) |
CSURI >2.94 vs <2.94 | 3.0 (1–19) vs 3.1 (1–11) | 1.8 (0–8) vs 2.6 (0–10) | 1.5 (0–10) vs 0.3 (0–1)* | 5.8 (2.3–14.5) vs 8.3 (4.0–12.0)* |