|
Females vs males
|
3.0 (1–19) vs 6.0 (3–9)
|
2.5 (0–10) vs 4.2 (0–8)
|
1.5 (0–10) vs 1.1 (0–3)
|
6.2 (2.3–14.5) vs 6.9 (5.9–7.9)
|
|
Diffuse vs limited
|
3.0 (1–11) vs 3.1 (1–19)
|
1.0 (0–8) vs 2.7 (0–10)
|
2.0 (0–10) vs 1.2 (0–9)
|
5.2 (2.3–14.5) vs 6.5 (3.0–12)
|
|
Anti-Scl70 vs ACA
|
1.8 (1–11) vs 3.4 (1–19)
|
2.8 (0–8) vs 2.7 (0–10)
|
1.8 (0–10) vs 1.5 (0–9)
|
4.9 (2.3–8.8) vs 6.1 (2.4–14.5)
|
|
Anti-Scl70 vs others
|
1.8 (1–11) vs 8.7 (1–19)
|
2.8 (0–8) vs 1.4 (0–10)
|
1.8 (0–10) vs 0.5 (0–2)
|
4.9 (2.3–8.8) vs 7.5 (4.0–14.5)
|
|
ACA vs others
|
3.4 (1–19) vs 8.7 (1–19)
|
2.7 (0–10) vs 1.4 (0–10)
|
1.5 (0–10) vs 0.5 (0–2)
|
6.1 (2.3–14.5) vs 7.5 (4.0–14.5)
|
|
No ulcers vs ulcers
|
3.2 (1–18) vs 3.0 (1–19)
|
2.7 (0–8) vs 2.0 (0–10)
|
1.5 (0–10) vs 1.4 (0–5)
|
6.1 (2.3–14.5) vs 5.9 (4.0–9.8)
|
|
No GE vs GE
|
5.7 (1–17) vs 2.8 (1–19)
|
1.6 (0–3) vs 3.0 (0–10)
|
1.0 (0–4) vs 1.5 (0–10)
|
6.9 (3.0–9.4) vs 6.0 (2.3–14.5)
|
|
sPAP < 45 mmHg vs > 45 mmHg
|
3.3 (1–19) vs 2.0 (1–3)
|
2.4 (0–10) vs 6.5 (0–8)
|
1.2 (0–9) vs 4.3 (2–10)*
|
6.3 (2.4–14.5) vs 5.2 (2.3–5.9)
|
|
DLCO < 50 % vs > 50 %
|
2.5 (1–7) vs 4.1 (1–19)
|
5.0 (0–8) vs 2.7 (0–10)
|
1.5 (0–4) vs 1.2 (0–10)
|
5.3 (4.6–14.5) vs 6.1 (2.3–12)
|
|
FVC < 80 % vs > 80 %
|
3.4 (1–19) vs 3.0 (2–9)
|
2.7 (0–10) vs 2.4 (0–8)
|
0.9 (0–9) vs 2.1 (0–10)
|
6.5 (2.3–14.5) vs 5.3 (2.3–7.9)
|
|
No honeycombing vs honeycombing
|
3.6 (1–19) vs 2.3 (1–3)
|
1.5 (0–10) vs 5.0 (1–6)
|
0.7 (0–4) vs 1.2 (0–10)
|
6.3 (4.0–9.9) vs 5.0 (2.3–14.5)
|
|
Skin score < 14 vs > 14
|
3.0 (1–19) vs 8.0 (1–11)
|
2.7 (0–10) vs 1.2 (0–8)
|
1.4 (0–9) vs 1.8 (0–10)
|
6.6 (2.4–12.0) vs 4.6 (2.3–14.5)
|
|
No iloprost vs iloprost
|
3.6 (1–19) vs 3.0 (1–16)
|
2.0 (0–8) vs 3.0 (0–10)
|
0.7 (0–3.4) vs 1.5 (0–10)*
|
6.1 (4.0–9.9) vs 6.1 (2.3–14.5)
|
|
No bosentan vs bosentan
|
3.4 (1–19) vs 2.0 (1–6)
|
1.8 (0–10) vs 5.8 (3–8)*
|
0.9 (0–10) vs 1.8 (2–4)
|
6.3 (2.3–14.5) vs 5.6 (5.0–8.8)
|
|
Early pattern vs others
|
0.5 (1–4) vs 3.3 (1–19)*
|
3.1 (1–10) vs 2.2 (0–10)
|
0.5 (0–1) vs 1.5 (0–10)*
|
9.5 (9.0–10.8) vs 5.9 (2.3–14.5)*
|
|
Active pattern vs others
|
8.0 (1–19) vs 1.6 (1–8)*
|
2.0 (0–10) vs 3.0 (0–10)
|
0.7 (0–3) vs 2.0 (0–10)*
|
6.9 (4.0–14.5) vs 5.3 (2.3–12.0)
|
|
Late pattern vs others
|
2.1 (1–7) vs 6.3 (1–19)*
|
2.7 (0–8) vs 2.4 (0–10)
|
2.1 (1–10) vs 0.5 (0–3)*
|
5.0 (2.3–9.8) vs 7.5 (4.0–14.5)*
|
|
VEGF-A <0.8U vs >0.8U
|
3.0 (1–19) vs 3.8 (1–9)
|
2.0 (0–10) vs 4.5 (0–6)
|
1.5 (0–10) vs 1.5 (0–3)
|
6.4 (2.3–12.0) vs 4.7 (4.0–14.5)
|
|
CSURI >2.94 vs <2.94
|
3.0 (1–19) vs 3.1 (1–11)
|
1.8 (0–8) vs 2.6 (0–10)
|
1.5 (0–10) vs 0.3 (0–1)*
|
5.8 (2.3–14.5) vs 8.3 (4.0–12.0)*
|
