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Table 2 The main statistical parameters of thyroid peroxidase autoantibodies, in males and females, measured by the five automated immunoassay methods

From: Establishment of the upper reference limit for thyroid peroxidase autoantibodies according to the guidelines proposed by the National Academy of Clinical Biochemistry: comparison of five different automated methods

Sex

No.

Mean (CI 95 %)

SD

CV

Median

p

eURL

mURL

Δ

IMM

 Males

120

8.2 (7.1–9.3)

6.0

73.6

6.4

0.8

28.7

35.0

18.0

 Females

120

8.9 (7.6–10.1)

7.0

79.6

6.7

29.0

17.1

MAG

 Males

120

5.5 (4.3–6.6)

6.5

119.8

2.7

0.8

24.6

30.0

18.0

 Females

120

4.9 (3.8–6.1)

6.2

126.3

2.2

25.4

15.3

KRY

 Males

120

2.7 (2.5–2.9)

1.4

50.6

2.6

0.6

6.4

10.5

39.0

 Females

120

2.6 (2.3–2.8)

1.2

48.6

2.4

6.9

34.3

PHA

 Males

120

2.8 (2.6–3.1)

1.4

50.9

2.6

<0.05

8.3

25.0

66.8

 Females

120

3.7 (3.1–3.8)

1.8

51.8

3.1

10.0

60.0

LIA

 Males

120

3.2 (2.6–3.9)

3.4

106.0

1.9

0.8

14.2

16.0

11.3

 Females

120

3.2 (2.6–3.9)

3.9

111.3

1.7

17.9

11.9

  1. CV and Δ are expressed in percentage; Mean, Median, SD, eURL and mURL are expressed in IU/mL. eURL = 99.0th ‰; Δ = mURL − eURL/mURL × 100
  2. CI confidence intervals, CV coefficient of variation, eURL experimental upper reference limit, IMM Immulite 2000 XPi, KRY Kryptor Compact Plus, LIA Liaison XL, MAG Maglumi 2000 Plus, mURL manufacturer’s upper reference limit, PHA Phadia 250, SD standard deviation