Table 4 Autoantibodies to stress proteins in liver disease
From: Autoantibodies in liver disease: important clues for the diagnosis, disease activity and prognosis
Autoantibodies | Molecular target | Associated liver disease | Clinical significance |
|---|---|---|---|
Anti-ox-LDL | ox-LDL | HCV | Correlation with hepatic steatosis |
Anti-MDA | MDA | HCV, NASH | Correlation with hepatic steatosis |
Anti-CYP2E1 | CYP2E1 | Type 1 AIH, HCV, alcohol, halothane-induced hepatitis | Â |
Anti-cardiolipin | Cardiolipin | Type 1 AIH, PBC, NASH, alcohol, HCV | IgG4 type of anti-CYP2E1 correlation with hepatic fibrosis |
HCV | |||
Anti-SOD | SOD | AIH, HCV | Correlation with anti-HSP65 |
Anti-HSP | HSP65 | AIH | Â |
| Â | HSP70 | HCV | Inverse correlation with disease-activity |