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TableĀ 2 Prognostic values of PBC-specific ANA

From: Autoantibodies in liver disease: important clues for the diagnosis, disease activity and prognosis

Immunofluorescent pattern Nuclear antigens Clinical significance
Rim-like/membranous gp210 nucleoporin/p62 lamin B receptor Progression to liver failure advanced liver stage
Multiple nuclear dots Sp100 Recurrent urinary tract infection
Sp140 Coexistence with anti-Sp100
PML Coexistence with anti-Sp100
Discrete speckled CENP-B Progression to portal hypertension