Fig. 1
From: Asialoglycoprotein receptor (ASGPR): a peculiar target of liver-specific autoimmunity
Prevalence of autoantibodies in children (n = 18, median of age 10 years) and adults (n = 28, median of age 46 years) with autoimmune hepatitis (AIH). Seropositivity for antinuclear antibodies (ANA), anti-smooth muscle antibodies (ASMA), liver–kidney microsomal type 1 (LKM-1) and anti-mitochondrial (AMA) antibodies were detected by indirect immunofluorescence on respective substrates. Antibodies to asialoglycoprotein receptor (ASGPR) and soluble liver antigen (SLA) were determined by commercial ELISA. 2 of 18 children with AIH suffered from type 2 AIH, whereas 2 of 28 adult patients with AIH demonstrated type 2 disease. All remaining patients had type 1 AIH. *P < 0.05