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Table 1 Diagnostic criteria for recurrent primary biliary cirrhosis (PBC) after liver transplantation (LT)

From: Recurrence of autoimmune liver diseases after liver transplantation: clinical aspects

Diagnostic criteria for recurrent PBC

LT performed for PBC

Persistence of AMA or anti-M2 antibody

Characteristic portal triad lesions on a liver biopsya

 Epithelioid granulomas

 Mononuclear inflammatory infiltrate

 Lymphoid aggregates

 Bile duct damage

Absence of other pathology/disorders, including:

 Acute and chronic rejection

 Graft versus host disease

 Biliary obstruction

 Vascular abnormalities

 Cholangitis and other infections

 Viral hepatitis

 Drug toxicity

  1. aThree of the four portal tract lesions need to be present, and at least three portal fields