From: The immunofluorescence techniques in the diagnosis of endocrine autoimmune diseases
Presence of autoantibodies and/or cell-mediated events in the serum |
Presence of lympho-monocyte infiltration in the target organs |
Possibility of identification and isolation of autoantigens |
Possibility of experimentally induction of the disease in animals by immunization with autoantigens and the transfer the disease passively by serum or lymphocytes |