Table 1 Nomenclature of HEp-2 cell staining patterns
From: Missing links in high quality diagnostics of inflammatory systemic rheumatic diseases
Membranous nuclear patterns |
 Smooth membranous nuclear |
 Punctate membranous nuclear |
Nucleoplasmic patterns |
 Homogeneous nucloplasmic |
 Large speckled nucleoplasmic |
 Coarse speckled nucleoplasmic |
 Fine speckled nucleoplasmic |
 Fine grainy Scl-70 like nucleoplasmic |
 Pleomorphic speckled (anti-PCNA) |
 Centromere |
 Multiple nuclear dots |
 Coiled bodies (few nuclear dots) |
Nucleolar patterns |
 Homogeneous nucleolar |
 Punctate nucleolar |
 Clumpy nucleolar |
Spindle apparatus patterns |
 Centriole (centrosome) |
 Spindle pole (NuMa/MSA-1) |
 Spindle fiber |
 Midbody (MSA-2) |
 CENP-F (MSA-3) |
Cytoplasmic patterns |
 Diffuse cytoplasmic |
 Fine speckled cytoplasmic |
 Mitochondrial-like |
 Lysosomal-like |
 Golgi-like |
 Contact proteins |
 Vimentin-like |
Negative |
Undeterminable |