Fig. 3From: In vivo effects of a human thyroid-stimulating monoclonal autoantibody (M22) and a human thyroid-blocking autoantibody (K1-70)Injection of K1-70 IgG into rats and serum levels of a K1-70 IgG, b total T4 and c free T4 (mean ± standard deviation; n = 5). Buffer only (filled diamond); 10 μg K1-70/rat (filled square); 50 μg K1-70/rat (filled triangle); 100 μg K1-70/rat (times symbol); 200 μg K1-70/rat (filled circle). All three parameters were measured in the same serum sample. The assay detection limits for total T4 and free T4 were <26 nmol/L and <6.4 pmol/L, respectivelyBack to article page