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Fig. 1 | Autoimmunity Highlights

Fig. 1

From: In vivo effects of a human thyroid-stimulating monoclonal autoantibody (M22) and a human thyroid-blocking autoantibody (K1-70)

Fig. 1

Injection of M22 IgG into T3-suppressed rats and serum levels of a M22 IgG, b total T4 and c free T4 (mean ± standard deviation; n = 5). Buffer only (filled diamond); 2 μg M22/rat (filled square); 4 μg M22/rat (filled triangle); 10 μg M22/rat (times symbol). All three parameters were measured in the same serum sample. The concentrations of total T4 and free T4 in all T3-suppressed rats injected with buffer only were below the detection limits of the assays, i.e. <26 nmol/L and <6.4 pmol/L, respectively

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