Differentiation of autoimmune pancreatitis from pancreas cancer: utility of anti-amylase and anti-carbonic anhydrase II autoantibodies

Table 5 Diagnostic value of serological markers for AIP diagnosis excluding idiopathic CP as control goup

	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)
Elevated IgG4 levels	58	95	58	95
CA-II Abs	83	81	34	98
AMY-α Abs	83	94	63	98
Elevated IgG4 levels and CA-II Abs	50	98	75	94
Elevated IgG4 levels and AMY-α Abs	50	100	100	94
CA-II Ab and AMY-α Abs	75	97	75	97
All three: elevated IgG4 levels, CA-II Ab and AMY-α Abs	50	100	100	94

AIP autoimmune pancreatitis, Abs autoantibodies, CAII anti-carbonic anhydrase II, AMY-α anti-amylase α, PPV positive predictive value, NPV negative predictive value

ISSN: 2038-3274