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Table 4 Diagnostic value of serological markers for AIP diagnosis

From: Differentiation of autoimmune pancreatitis from pancreas cancer: utility of anti-amylase and anti-carbonic anhydrase II autoantibodies

 

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

Elevated IgG4 levels

58

94

50

96

CA-II Abs

83

75

24

98

AMY-α Abs

83

89

42

98

Elevated IgG4 levels and CA-II Abs

50

98

67

95

Elevated IgG4 levels and AMY-α Abs

50

99

86

95

CA-II Abs and AMY-α Abs

75

93

50

98

All three: elevated IgG4 levels, CA-II Abs and AMY-α Abs

50

99

86

95

  1. AIP autoimmune pancreatitis, Abs autoantibodies, CAII anti-carbonic anhydrase II, AMY-α anti-amylase α, PPV positive predictive value, NPV negative predictive value