Table 4 Sensitivity, specificity, PPV and NPV of tests
From: Assessment of a combination screening assay for celiac disease
h-tTG/DGP Screen | IgA a-tTG | IgG a-tTG | IgA a-DGP | IgG a-DGP | EMA IgA | |
|---|---|---|---|---|---|---|
% Sensitivity (95% CI) | 100 | 100 | 78.05 | 90.24 | 87.80 | 100 |
(76.78–79.32) | (89.34–91.15) | (86.80–88.81) | ||||
% Specificity (95% CI) | 91.12 | 98.82 | 82.25 | 97.04 | 95.86 | 100 |
(90.70–91.55) | (98.65–98.98) | (81.67–82.82) | (96.79–97.30) | (95.56–96.16) | ||
% PPV (95% CI) | 73.21 | 95.35 | 51.61 | 88.10 | 83.72 | 100 |
(72.05–74.37) | (94.72–95.98) | (50.37–52.86) | (87.12–89.07) | (82.6 2–84.82) | ||
% NPV (95% CI) | 100 | 100 | 93.92 | 97.62 | 97.01 | 100 |
(93.53–94.30) | (97.31–97.85) | (96.75–97.26) |