Table 2 Distribution of IIF patterns and specificities of autoantibodies in 112 Italian patients
IIF patterns and specificities of autoantibodies | N/total (%) | Diffuse N/total (%) | Limited N/total (%) | p |
|---|---|---|---|---|
Positive IIF ANA | 109 (97) | 45 (96) | 64 (98) | ns |
Diffuse grains | 47 (42) | 23 (49) | 24 (37) | ns |
ACA | 36 (32) | 8 (17) | 28 (43) | <0.01 |
Speckled | 10 (8.9) | 6 (13) | 4 (6) | ns |
Nucleolar | 11 (9.8) | 5 (11) | 6 (9) | ns |
Homogeneous | 5 (4.5) | 3 (6) | 2 (3) | ns |
Mitotic spindle apparatus | 2 (1.7) | 1 (2) | 1 (1.5) | – |
Cytoplasmic | 4 (3.6) | 1 (2) | 3 (5) | – |
More than one positive IIF pattern | 11 (9.8) | 3 (6) | 8 (12) | ns |
Specificities identified | ||||
Anti-SCl70 | 48 (43) | 24 (51) | 24 (37) | ns |
Anti-CENPB | 36 (32) | 8 (17) | 28 (43) | <0.01 |
Anti-histones | 13 (11.6) | 4 (8.5) | 9 (14) | ns |
Anti-RNA pol III | 8 (7.1) | 4 (8.5) | 4 (6) | ns |
Anti-PM/SCL | 4 (3.5) | 3 (6.3) | 1 (1.5) | – |
Anti-fibrillarin | 2 (1.8) | 1 (2) | 1 (1.5) | – |
Anti-Ku | 1 (0.9) | 1 (2.1) | – | – |